The InkJet technique was normally used in ink printers and has experienced a massive developement since the 1950’s. At present, it is also used in preparation of printed circuits, 3D printing, cover layering and other high-tech methods of modern industry.
InkJet technique is based on a nozzle system able to generate small liquid droplets. The droplet size is dependent on the type of the InkJet printhead and on the properties of dropped liquid, but in general it does not exceed 100 μm in diameter. The so-called Drop-on-Demand printhead with a piezoelectric actuator is used in our work. The principle of Drop-on-Demand printing is the following: a volume change in a small capillary caused by an actuator (piezoelectric in our case) ejects the liquid from the capillary outlet. The liquid then creates a small droplet at the orifice of the capillary due to surface tension.
The aim of our work is to use the InkJet Drop-on-Demand technique for reproducible laboratory-scale fabrication of calcium alginate microcapsules, including those containing inner inclusions (liposomes, yeast). Particle size in the range of 30–90 μm can be achieved depending on the alginate concentration and inkjet parameter settings. The advantages of the inkjet method are reproducibility of particle size, ability to work with small volumes (beneficial especially in early-stage prototyping) and relatively benign conditions (low shear rates, atmospheric pressure, room temperature). The InkJet printhead from Microfab Corporation (type M5-ABP-01) is used throughout our work.
- Ullrich M., Hanuš J., Dohnal J., Štěpánek F., “Encapsulation stability and temperature-dependent release kinetics from hydrogel-immobilised liposomes”, J. Coll. Interf. Sci. 394, 380-385 (2013)
- Haufová P., Dohnal J., Hanuš J., Štěpánek F., “Towards the inkjet fabrication of artificial cells”, Coll. Surf. A 410, 52-58 (2012)
- Dohnal J., Štěpánek F., “Fabrication of composite microcapsules by drop-on-demand inkjet: Effect of precursor composition on the process limits”, Chem. Eng. Sci. 66, 3829-3835 (2011)
- Dohnal J., Štěpánek F., “Inkjet fabrication and characterisation of calcium alginate microcapsules”, Powder Technol. 200, 254-259 (2010)